IN190080B - - Google Patents
Info
- Publication number
- IN190080B IN190080B IN95MU2001A IN190080B IN 190080 B IN190080 B IN 190080B IN 95MU2001 A IN95MU2001 A IN 95MU2001A IN 190080 B IN190080 B IN 190080B
- Authority
- IN
- India
- Prior art keywords
- azithromycin
- solvent
- azithromycin dihydrate
- hygroscopic
- dihydrate
- Prior art date
Links
- VQEMDSRIOVZAOM-UHFFFAOYSA-N 4-(4-methylsulfonylphenyl)-1,3-thiazol-2-amine Chemical compound C1=CC(S(=O)(=O)C)=CC=C1C1=CSC(N)=N1 VQEMDSRIOVZAOM-UHFFFAOYSA-N 0.000 abstract 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 229960004924 azithromycin dihydrate Drugs 0.000 abstract 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 229960004099 azithromycin Drugs 0.000 abstract 1
- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 229960004592 isopropanol Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN95MU2001 IN190080B (en]) | 2001-01-29 | 2001-01-29 | |
US10/050,897 US20020111318A1 (en) | 2001-01-29 | 2002-01-18 | Process for the preparation of non-hygroscopic azithromycin dihydrate |
DE60200298T DE60200298T2 (de) | 2001-01-29 | 2002-01-23 | Verbessertes Verfahren zur Herstellung von non-hygroscopischem Azithromycin Dihydrat |
EP02001530A EP1227102B1 (en) | 2001-01-29 | 2002-01-23 | An improved process for the preparation of non-hygroscopic azithromycin dihydrate |
AT02001530T ATE263182T1 (de) | 2001-01-29 | 2002-01-23 | Verbessertes verfahren zur herstellung von non- hygroscopischem azithromycin dihydrat |
ES02001530T ES2218476T3 (es) | 2001-01-29 | 2002-01-23 | Procedimiento mejorado para preparar dihidrato de acitromicina no higroscopico. |
CA002369255A CA2369255C (en) | 2001-01-29 | 2002-01-24 | An improved process for the preparation of non-hygroscopic azithromycin dihydrate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN95MU2001 IN190080B (en]) | 2001-01-29 | 2001-01-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN190080B true IN190080B (en]) | 2003-06-07 |
Family
ID=11097214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN95MU2001 IN190080B (en]) | 2001-01-29 | 2001-01-29 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20020111318A1 (en]) |
EP (1) | EP1227102B1 (en]) |
AT (1) | ATE263182T1 (en]) |
CA (1) | CA2369255C (en]) |
DE (1) | DE60200298T2 (en]) |
ES (1) | ES2218476T3 (en]) |
IN (1) | IN190080B (en]) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6861413B2 (en) | 2001-05-22 | 2005-03-01 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
AP2003002906A0 (en) | 2001-05-22 | 2003-12-31 | Pfizer Prod Inc | Crystal forms of azithromycin |
US6855813B2 (en) * | 2002-07-19 | 2005-02-15 | Alembic Limited | Process for the preparation of azithromycin monohydrate |
GB2395482A (en) * | 2003-07-03 | 2004-05-26 | Jubilant Organosys Ltd | Process for preparing non-hygroscopic azithromycin dihydrate |
KR100844628B1 (ko) * | 2003-12-04 | 2008-07-07 | 화이자 프로덕츠 인크. | 제약상 다입자의 제조 방법 |
WO2005053652A1 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride |
US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
US7683162B2 (en) * | 2004-08-30 | 2010-03-23 | Taro Pharmaceutical Industries Limited | Process of preparing a crystalline azithromycin monohydrate |
US20090318375A1 (en) * | 2005-06-08 | 2009-12-24 | Hanmi Pharm Co., Ltd | Crystalline Azithromycin L-Malate Monohydrate and Pharmaceutical Composition Containing Same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989000576A1 (en) * | 1987-07-09 | 1989-01-26 | Pfizer Inc. | Azithromycin dihydrate |
CN1093370A (zh) * | 1993-12-10 | 1994-10-12 | 北京市集才药物研究所 | 一种新的阿齐红霉素结晶及其制备方法 |
PT102130A (pt) * | 1998-03-13 | 1999-09-30 | Hovione Sociedade Quimica S A | Processo de preparacao de dihidrato de azitromicina |
ES2177373B1 (es) * | 1999-11-26 | 2003-11-01 | Astur Pharma Sa | Preparacion de azitromicina en su forma no cristalina |
-
2001
- 2001-01-29 IN IN95MU2001 patent/IN190080B/en unknown
-
2002
- 2002-01-18 US US10/050,897 patent/US20020111318A1/en not_active Abandoned
- 2002-01-23 ES ES02001530T patent/ES2218476T3/es not_active Expired - Lifetime
- 2002-01-23 EP EP02001530A patent/EP1227102B1/en not_active Expired - Lifetime
- 2002-01-23 AT AT02001530T patent/ATE263182T1/de not_active IP Right Cessation
- 2002-01-23 DE DE60200298T patent/DE60200298T2/de not_active Expired - Lifetime
- 2002-01-24 CA CA002369255A patent/CA2369255C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE263182T1 (de) | 2004-04-15 |
DE60200298T2 (de) | 2005-05-04 |
EP1227102A1 (en) | 2002-07-31 |
DE60200298D1 (de) | 2004-05-06 |
ES2218476T3 (es) | 2004-11-16 |
EP1227102B1 (en) | 2004-03-31 |
CA2369255C (en) | 2007-04-03 |
US20020111318A1 (en) | 2002-08-15 |
CA2369255A1 (en) | 2002-07-29 |
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